Bile acid metabolism in infants and children.
نویسندگان
چکیده
منابع مشابه
Inborn Errors of Bile Acid Metabolism
Bile acids are synthesized by the liver from cholesterol through a complex series of reactions involving at least 14 enzymatic steps. A failure to perform any of these reactions will block bile acid production with failure to produce ‘‘normal bile acids’’ and, instead, result in the accumulation of unusual bile acids and intermediary metabolites. Failure to synthesize bile acids leads to reduce...
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The metabolism of bile acids in 30 pregnant women was evaluated by analyzing the urinary composition of bile acids during late gestation (weeks 30-41) and again in these women and their newborn infants during the first week after delivery. The levels of individual bile acids were determined by gas chromatography-mass spectrometry after solvolysis and hydrolysis of bile acid conjugates. The mean...
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Introduction: Liver disease results in complex pathophysiologic disturbances affecting nutrient digestion, absorption, distribution, storage, and use. This article aimed to present a classification of metabolic disturbances in chronic liver disease in children? Materials and Methods: In this review study databases including proquest, pubmedcentral, scincedirect, ovid, medlineplus were been se...
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Recognition of neonatal liver disease has been heavily dependent on the occurrence of jaundice. In most instances the jaundice is related to specific disturbances in bilirubin transport and other tests of liver function are normal. In contrast, hepatitis and other liver diseases not specifically affecting bilirubin transport often go undetected unless jaundice occurs. The development of practic...
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Aims—To investigate whether a fetal pathway of bile acid synthesis persists in neonates and infants. Methods—3-oxo-Ä bile acids were determined qualitatively and quantitatively in the urine, meconium, and faeces of healthy neonates and infants, using gas chromatography–mass spectrometry. Results—The mean percentage of 3-oxo-Ä bile acids in total bile acids in urine at birth was significantly hi...
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عنوان ژورنال:
- Clinics in gastroenterology
دوره 6 1 شماره
صفحات -
تاریخ انتشار 1974